Services

Therapeutic oligonucleotides:

• AntiSense Oligonucleotide

• small interfering RNA

• microRNA

• Aptamer

• sgRNA for CRISPR/Cas

• Immunostimulatory agent (e.g. CPG7909)

• DNA decoy

• Modified oligo, e.g. GalNAc, cholesterol, lipid, disulfide, PEG

Diagnostic oligonucleotides:

• Highly modified DNA/RNA

• Primer/probe

• Ultra long RNA/DNA , e.g. up to 200mer

• Circular RNA/DNA

Research oligonucleotides:

• FISH/MERFISH probes

• Branched/dendrimer oligos

• DNA-encoded library (DEL)

• Custom conjugation/post labeling

• Special modified oligo, e.g. dye, lipid, linkers, photo-cleavable, small molecule, peptide, carbohydrate

• Raw material (e.g. solid support, phosphoramidite, linker, conjugate)

• Vendor qualification

• Process development for drug substance or API manufacturing

• Analytical method development for drug substance and drug product

• Technical writing and review

• Proposal review and negotiation

• Clinical material supply